APOE4 & Alzheimer’s Prevention | Brain Health Science

My APOE4/4 Senolytic Protocol: Intermittent pulsing of Fisetin/Quercetin/Dasatinib to kill off "zombie" cells.

Why Senescent Cells Belong in the APOE4 Conversation

Jan 8 • Karin Dee

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December 2025

Botox and APOE4:

This post reviews what Botox actually does (and does not do), why it doesn’t interact with APOE4 biology, what decades of safety data show, and where…

Dec 29, 2025 • Karin Dee

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Rapamycin and APOE4:

APOE4 alters brain biology decades before Alzheimer’s symptoms appear. This deep dive examines rapamycin, mTOR inhibition, animal and human evidence…

Dec 19, 2025 • Karin Dee

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APOE4 and Statins: What Recent Science Actually Shows

(And why the biggest protective effect appears in E4 carriers, not everyone else)

Dec 8, 2025 • Karin Dee

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November 2025

Thyroid Hormones, Genes and APOE4

How DIO1 and DIO2 SNPs can quietly sabotage T4→T3 conversion, cognitive health, and sleep

Nov 28, 2025 • Karin Dee

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Phase Separation: Something Every APOE4 Carrier Needs to Know About

What it is, why it matters, and how we can influence it!

Nov 21, 2025 • Karin Dee

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Melatonin, Heart Failure, and Alzheimer’s: What This Week’s Headlines Got Wrong

Headlines screamed: “Melatonin users are more likely to develop heart failure and die.”

Nov 12, 2025 • Karin Dee

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Why Everyone at Midlife Should Have a Baseline Memory Test

Get yours today, and free online!!

Nov 5, 2025 • Karin Dee

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October 2025

A New Dawn in Alzheimer’s Research: Gene Editing Collaboration Between Form Bio & Weill Cornell Medicine

Moving in the right direction ....

Oct 30, 2025 • Karin Dee

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New research may finally explain the “why” behind APOE4’s danger — and offers clues to prevention.

Why APOE4 Raises Alzheimer’s Risk — and What It Really Means for Brain Metabolism

Oct 23, 2025 • Karin Dee

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The Researcher Who Shook Up APOE4 Science — Live Q&A This Friday

If you follow Alzheimer’s research, you’ve likely heard the name Dr.

Oct 22, 2025 • Karin Dee

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The Nighttime Spice Ritual: Protecting the Brain, Heart & APOE4 Genes Through a Healthy Mouth

How supporting your oral microbiome can quiet inflammation, boost nitric oxide, and lower Alzheimer’s and cardiovascular risk

Oct 16, 2025 • Karin Dee

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