The APOE4 Gene | Brain Health & Alzheimer’s Prevention

The APOE4 Gene | Brain Health & Alzheimer’s Prevention

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September 2025

Rapamycin (generic: Sirolimus) for APOE4: a Preventive Play Aimed at Brain Energy + Blood Flow
Mounting evidence pointing towards its efficacy in protecting the brain.
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Karin Dee
1
Nattokinase: A Natural Ally for Brain Health in APOE4 Carriers
How a traditional Japanese enzyme may protect APOE4 carriers from silent strokes, inflammation, and Alzheimer’s pathology
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Karin Dee
News Out of Stanford
Rethinking Alzheimer’s: Why this common gene variant is bad for your brain
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Karin Dee
Could Fixing Brain Energy Reverse Alzheimer’s?
Recent work by Dr.
 • 
Karin Dee
GLP-1 Medicines: What the Science Says About Alzheimer’s Risk Reduction
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) like semaglutide (Ozempic/Wegovy) and liraglutide (Victoza/Saxenda) were built for diabetes and…
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Karin Dee
1

August 2025

Think Twice Before Reaching for That OTC Drug
If you (or a loved one) don't use any, you can skip this post.....
 • 
Karin Dee
1
New, Potentially Significant, Research!
Study identifies a functional impairment in cholesterol delivery via CSF lipoproteins
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Karin Dee
3
Cyclodextrins: A Surprising Ally for APOE4 Brain & Heart Health
If you’ve been following my writing, you know that one of my biggest interests is how to protect brain and vascular health in people with the APOE4 gene…
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Karin Dee
4
Could Lithium Save the Brain?
In a thought‑provoking analysis, Science explores whether lithium could offer a new avenue in the fight against Alzheimer’s—a direction prompted by…
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Karin Dee
Clearing the Clutter:
Why Senescent Cells Matter in the Fight Against Alzheimer’s
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Karin Dee
1
Mindfulness and Brain Aging
While aging affects everyone differently, maintaining a brain-healthy lifestyle—anchored by mindful awareness—is key to supporting cognitive health.
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Karin Dee
© 2025 Karin Dee
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