APOE4 & Alzheimer’s Prevention | Brain Health Science

A Deeper Dive Into the Results From My RetainMed Visit

Taking a closer look at my amyloid, tau, GFAP, NfL, genetics and other biomarkers—and what they may mean going forward.

Oct 1 • Karin Dee

22

10

1

September 2026

Obicetrapib: Why There Is So Much Excitement Over The Release Of This Drug.

If you’ve been following my writing for a while, Obicetrapib is a name you’ve become familiar with.

Sep 24 • Karin Dee

19

4

1

Obicetrapib Just Received European Approval

Some very exciting news for those of us who have been following obicetrapib, the new oral CETP inhibitor developed by NewAmsterdam Pharma.

Sep 21 • Karin Dee

16

2

1

A New Clue Emerges How APOE4 Damages the Blood-Brain Barrier

New research identifies fibronectin as a potential link between APOE4, inflammation and blood-brain barrier dysfunction—and points toward some…

Sep 17 • Karin Dee

13

12

3

Interesting New APOE4 Research Which Takes Me Back to Dr. Alan Green and Rapamycin

Protecting the Blood Brain Barrier

Sep 3 • Karin Dee

21

10

3

August 2026

My Results Are In!

Eight Years Into Alzheimer’s Prevention

Aug 27 • Karin Dee

43

40

1

Humanin: A neuroprotective cell regulator assistant

A tiny peptide with big potential.

Aug 20 • Karin Dee

12

4

p-Tau217: Is the Alzheimer's Blood Test like a looking glass portending the future?

For those of us at increased genetic risk for Alzheimer’s disease - I know the dilemma!

Aug 13 • Karin Dee

33

7

1

CETP - A New Target That May Be a Game-Changer for APOE4!

For years, CETP (Cholesteryl Ester Transfer Protein) has been viewed as a cardiovascular target - it's gaining promising attention in a new way!

Aug 6 • Karin Dee

22

5

4

July 2026

Why Rapamycin May Be Uniquely Protective in APOE4:

The CypA–MMP-9–BBB Pathway Explained

Jul 30 • Karin Dee

22

9

2

APOE4 and the Mitochondrial Glutathione Question

Why the APOE4 brain may be uniquely vulnerable to oxidative stress - and how that could impact AD prevention

Jul 23 • Karin Dee

30

9

4

Our Brains Hoard Vitamin C. Here's Why That Should Grab Our Attention.

A new study just landed, and it’s the kind of finding that makes you put down your coffee and reread the numbers twice.

Jul 16 • Karin Dee

29

11

5