APOE4 & Alzheimer’s Prevention | Brain Health Science
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NAD: the energetic “permission signal” behind membrane repair
NAD and APOE4: Why Cellular Energy May Be the Missing Layer in Lipid Trafficking Resilience
Feb 26
•
Karin Dee
13
5
1
APOE4, the Gut Microbiome, and the Missing Piece in Lipid Transport
How gut microbiome differences in APOE4 carriers may influence neuroinflammation — and practical steps to reduce risk
Feb 19
•
Karin Dee
23
8
2
Triglycerides: The Goldilocks Problem
Triglycerides have become the lipid we love to hate.
Feb 12
•
Karin Dee
9
5
1
Could Lithium Be a Missing Piece in Alzheimer’s Disease? A New Research Perspective
I’ve briefly touched on Lithium before - but it’s in the news again.
Feb 5
•
Karin Dee
15
9
2
January 2026
Calling all APOE4/4s - Input needed!
Calling APOE4/4 carriers
Jan 30
•
Karin Dee
4
2
Saffron, MCT C8 Powder and Reclaiming Metabolic Health
My N=1 Observation of Restored Glucose Metabolism
Jan 29
•
Karin Dee
15
14
2
Lipid Replacement Therapy (LRT): Rebuilding Cell Membranes From the Ground Up
The Structural Foundation Behind Cellular Energy, Signaling, and Brain Health
Jan 22
•
Karin Dee
15
5
1
APOE4 Is Revealing Its Hand
Why lipid trafficking has emerged as the most coherent target — and how I’m responding
Jan 17
•
Karin Dee
33
6
2
My APOE4/4 Senolytic Protocol: Intermittent pulsing of Fisetin/Quercetin/Dasatinib to kill off "zombie" cells.
Why Senescent Cells Belong in the APOE4 Conversation
Jan 8
•
Karin Dee
25
7
2
December 2025
Botox and APOE4:
This post reviews what Botox actually does (and does not do), why it doesn’t interact with APOE4 biology, what decades of safety data show, and where…
Dec 29, 2025
•
Karin Dee
3
Rapamycin and APOE4:
APOE4 alters brain biology decades before Alzheimer’s symptoms appear. This deep dive examines rapamycin, mTOR inhibition, animal and human evidence…
Dec 19, 2025
•
Karin Dee
16
2
APOE4 and Statins: What Recent Science Actually Shows
(And why the biggest protective effect appears in E4 carriers, not everyone else)
Dec 8, 2025
•
Karin Dee
93
55
16
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