The Researcher Who Shook Up APOE4 Science — Live Q&A This Friday
If you follow Alzheimer’s research, you’ve likely heard the name Dr. Juan Fortea — the neurologist whose provocative 2024 study in Nature Medicine sent shockwaves through the scientific community by proposing that APOE4 homozygosity should be redefined as a genetic cause of Alzheimer’s disease rather than simply a risk factor.
His conclusion challenged decades of conventional thinking — and not without controversy. The paper sparked intense debate, with some researchers pushing back against what they viewed as a paradigm shift in how Alzheimer’s should be classified and understood.
For those of us carrying two APOE4 alleles, Dr. Fortea’s work changed the conversation — from “if” we might develop Alzheimer’s to “how soon” and what we can do to intervene.
In this rare and first-ever public appearance, Dr. Fortea will engage with a global audience in a free webinar + Q&A hosted by the APOE4 Alzheimer’s Alliance:
📅 Friday, October 24, 2025
🕛 Noon ET
In the session, he’ll explore:
The origin story behind his landmark research
The latest insights into APOE4 biology and prevention strategies for high-risk carriers
Emerging therapies that give him genuine optimism about transforming outcomes in the near future
Watch the full interview with Dr. Fortea here:
Dr. Juan Fortea Interview — “Redefining APOE4”
Register for the live webinar (free):
https://apoe4alzheimersalliance.org/webinar-dr-fortea
If APOE4 touches your life or the life of someone you love, this is a conversation you won’t want to miss.
See you there ❤️

