40 Comments
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Shay's avatar

That’s great news Karin! I sure wish I could get into Dr. Isaacson’s clinic in Boca raton…. I have been trying for months. I have high ptau 217 and feel a sense of urgency. Lauren G says there is no current openings.

Karin Dee's avatar

Sounds like they filled up pretty fast! Did you do other markers or just ptau217?

Shay's avatar

What other biomarker test besides ptau 217 ? There were 17 tubes of blood drawn a year ago…. I am hopeful I can decrease my ptau 217 now that my cholesterol and apo b is in better shape …. Need to Excersize more.

Shay's avatar

I have a phone appointment with better brain next week they do some testing so I’ll learn more but it’s not ideal. I just need a preventative neurologist testing - AI suggested trials. Idk

Karin Dee's avatar

The brain-specific biomarkers AlzLabs/RetainMed does are: p-Tau217, p-Tau181, Aβ42, Aβ40, Aβ-42/Aβ40 ratio, p-Tau181/Aβ-42 ratio, pTau217/Aβ-42 ratio, NfL, GFAP.

Shay's avatar

I have reached out to both with no success. I’ll keep trying. I don’t know why this is so difficult I’m willing to pay - I’m very frustrated at this point and not feeling patient. Did you do 23 and me gene testing and get your raw data?

Karin Dee's avatar

yes, I did 23andme which is how I found out I'm 4/4. The 3 DNA tests done by RetainMed included confirmation of 4/4, MTHFR and Klotho.

Shay's avatar

Raw data on 23 and me also shows those why didn’t retain med use those especially since Isaacson endorses 23 and me ? Weird

Shay's avatar

My Functional Medicine doctor did a lot of tests, but she knows very little

about Apoe4/4’s and has given me nobody other than a lot supplements, diet,Excersize. I have 23 and me raw data. Looks like I have Klotho gene but really other than that. I don’t know how to read it. I just listened to a lot of podcast to try to educate myself and follow you. You’re inspiring. I would really like to get into retain med in Boca Raton.

Dr. Dorota Kossowska-Kühn's avatar

Congratulations! And thank you for sharing your personal story. For many people this will be much convincing than all the lectures/ posts based on the science only.

Rose Hackenbruck's avatar

This is great news!! Congratulations and thank you for your hard work and inspiration!

Mary's avatar

Congratulations! It is reassuring that diligence and effort have rewards. I too have followed all I can to keep myself healthy, including reading the latest research and developments. Thank you for contributing to this knowledge!

Dr Mark Chern's avatar

Lovely results! I also feel the relief!

Papi Jack's avatar

Order for post DOC thanks again

Lisa Hulin's avatar

Congratulations on the wonderful news!! Thank you for all you share. You are truly an inspiration.

CB's avatar

Inspiring! Great news!

Alexander MacInnis's avatar

So glad to hear your good news!

Priscilla F.'s avatar

Congrats! I look forward to hearing the rest of your news!

Lindsay Barnhart's avatar

My father had dementia and a fall and broken hip need his life at 86 years old. My mom is 94 with hearing and eye sight impairments and mild cognitive function. I will be 70 early next year and worry because of heavy drinking in my younger years and benzodiazapines use over the past 5 years. Would like to get tested for hereditary gene and to my dismay, found out Zanax causes a 50 percent increase in the risk of developing Alzheimer's. Currently trying to slow taper from benzos, but the withdrawal is brutal. Any suggestions for a positive game plan going forward?

Karen Kroupa's avatar

Wonderful news and validation that your efforts are on target and working! It doesn't get much better than that. So happy for you!

Barbara's avatar

I am thrilled for you! You are an inspiration for all of us trying to live this lifestyle. Look forward to your follow-up. Congratulations!

Laura Ford's avatar

What level do you keep your apob?

Karin Dee's avatar

Mine was at 55 and Dr. Isaacson's target is <55. I'll include more detail and targets in my follow up post.

Shannon's avatar

Amazing news, congratulations! I’m not brave enough to get tested yet!

Karin Dee's avatar

know the feeling - wasn't willing to test either without someone who would walk me through the results step by step!

Rose Hackenbruck's avatar

Congratulations Karin!!!! I’m

So happy for you and thanks for being such a force of knowledge and inspiration!